Semaglutide Side Effects: What's Normal (And What's Not)

Let's talk about the elephant in the room. Yes, semaglutide has side effects. But here's what nobody tells you about what's actually normal.

Common Semaglutide Side Effects

Okay, let's dive into the most common side effects. Nausea, constipation, diarrhea, and vomiting are the usual suspects. Most people get at least a little queasy, especially when starting.

Nausea

Nausea is the #1 complaint. It's worst when you first start or increase your dose. Your stomach's like, "Whoa, what was that?!"

How to manage it: Eat smaller meals, avoid greasy foods, and stay hydrated. Some people swear by ginger ale or anti-nausea meds.

Constipation

Semaglutide slows down digestion, which can lead to constipation. Fun times.

How to manage it: Drink plenty of water and eat fiber-rich foods. A stool softener can also help things move along.

Diarrhea

On the flip side, some people get diarrhea. It's less common than constipation, but still a possibility.

How to manage it: Stay hydrated and avoid foods that trigger it. Over-the-counter anti-diarrheal meds can provide relief.

Vomiting

Vomiting is less common but can happen, especially if you overeat.

How to manage it: Stick to smaller meals and avoid lying down after eating. If it's severe, talk to your doctor.

When to Worry

Most side effects are manageable, but some need medical attention.

• Severe abdominal pain: Could be pancreatitis or gallbladder issues.
• Persistent vomiting: Can lead to dehydration and electrolyte imbalances.
• Signs of pancreatitis: Severe abdominal pain, nausea, vomiting, fever.
• Vision changes: Rare, but needs immediate attention.

Tips to Minimize Side Effects

Here are some general tips to make the ride smoother:

• Start low, go slow: Follow your doctor's dosage schedule.
• Stay hydrated: Drink plenty of water.
• Eat small, frequent meals: Avoid overloading your stomach.
• Avoid greasy foods: They can worsen nausea.
• Listen to your body: If something feels wrong, call your doctor.

The Bottom Line

Semaglutide side effects are common, but usually manageable. Know what to expect, how to handle it, and when to seek medical help.