Managing GLP-1 Medication Side Effects
Evidence-based strategies to minimize discomfort and optimize your experience with GLP-1 weight loss medications.
Understanding GLP-1 Side Effects
While GLP-1 medications are highly effective for weight loss, they can cause side effects, particularly in the first few weeks. The good news is that most side effects are manageable and often diminish as your body adjusts to the medication.
Essential Guides for Side Effect Management
Managing Nausea on GLP-1 Medications
Practical strategies to minimize and manage nausea, the most common side effect of GLP-1 medications.
Preventing and Treating GI Side Effects
Complete guide to managing digestive issues including diarrhea, constipation, and stomach discomfort.
When to Call Your Doctor: Warning Signs
Important information on serious side effects and when to seek immediate medical attention.
Optimizing Your Experience on GLP-1s
Tips and strategies to maximize benefits while minimizing side effects for the best possible outcomes.
Most Common Side Effects & Solutions
Nausea (44-58%)
The most common side effect, usually mild to moderate and improves over time.
Solutions: Eat smaller meals, avoid fatty foods, stay hydrated, take medication before bed.
Diarrhea (30-40%)
Digestive system adjusts to slowed gastric emptying.
Solutions: Increase fiber gradually, stay hydrated, avoid trigger foods, consider probiotics.
Constipation (20-24%)
Slowed GI motility can lead to infrequent bowel movements.
Solutions: Increase water and fiber intake, regular exercise, consider stool softeners if needed.
Fatigue (11-15%)
Reduced calorie intake and body adjustments can cause temporary tiredness.
Solutions: Ensure adequate protein and nutrient intake, maintain sleep schedule, gentle exercise.
When to Seek Medical Attention
•Severe abdominal pain that doesn't improve
•Persistent vomiting preventing hydration
•Signs of pancreatitis (severe upper abdominal pain radiating to back)
•Vision changes or severe headache
•Signs of allergic reaction (rash, difficulty breathing, swelling)
Need Support with Side Effects?
Trimi's healthcare team provides ongoing support to help you manage side effects and optimize your GLP-1 therapy experience.
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