Switch from Sesame Care to Trimi: Simpler GLP-1 Access

Understanding the Sesame Care GLP-1 Model

Sesame Care occupies a unique niche in the telehealth space: it is a healthcare marketplace rather than an integrated care provider. On Sesame, patients browse independent providers, book appointments at transparent per-visit prices, and receive prescriptions that they then fill through their own pharmacy or a pharmacy the provider recommends. This model has genuine advantages — particularly the ability to select specific providers and the transparent per-visit pricing for episodic care.

For GLP-1 treatment, however, the marketplace model creates friction that an integrated telehealth provider like Trimi eliminates. GLP-1 therapy is ongoing — patients require regular medication refills, periodic dose adjustments, and consistent clinical oversight for 12–24+ months. A model designed for episodic consultations adds cost and complexity to what should be a streamlined monthly process.

Where the Sesame Model Creates Friction for GLP-1 Patients

Per-Visit Fees Add Up

Every interaction with your Sesame provider is a billable appointment. Initial consultation: $40–$90. Three-month follow-up: $30–$60. Dose adjustment request: $30–$60. If you need to change your dose twice in a year and have two scheduled check-ins, that is 4–5 appointments at $30–$90 each, plus your monthly medication costs. These visit fees have no ceiling — they accumulate as long as you are in treatment.

Trimi includes all provider interactions in the flat monthly fee. Dose adjustments, questions, check-ins — everything is covered at $99 or $125 per month.

Medication Is a Separate Transaction

Sesame provides the prescription; you handle the pharmacy. This requires identifying a compounding pharmacy, verifying its accreditation, placing orders, and managing your own refill schedule. For patients comfortable navigating the pharmacy landscape, this is manageable. For most, it is an additional layer of complexity and often a source of treatment gaps.

Trimi handles medication sourcing and delivery as part of the monthly subscription. Your vial ships monthly without you managing the pharmacy relationship separately. This is one of the key reasons Trimi patients have lower rates of treatment gaps and dose interruptions.

No Automatic Ongoing Oversight

On Sesame, there is no automatic check-in between visits. If you experience a side effect, plateau, or question between appointments, you either wait for your next scheduled visit or pay for an additional consultation. Trimi's model includes asynchronous provider messaging that is available and included — no extra charge.

The Integrated Model: How Trimi Works

Trimi is purpose-built for GLP-1 treatment. The patient journey is:

1. Complete online intake (10–15 minutes, no appointment required)
2. Provider review within 24 hours — asynchronous, no scheduling needed
3. Prescription issued and transmitted to accredited compounding pharmacy
4. Medication shipped within 5–8 business days of intake completion
5. Automatic monthly refills on a consistent schedule
6. Ongoing provider access for questions, dose changes, and check-ins — all included

This model eliminates the scheduling bottleneck, removes per-visit fees, and handles the pharmacy relationship — three of the main pain points Sesame Care patients report when managing GLP-1 therapy through a marketplace model.

Comparing Total Annual Costs

A reasonable estimate for a Sesame Care GLP-1 patient's annual costs:

• Initial consultation: $60
• 3 quarterly follow-up visits: $120–$180
• 2 dose adjustment consultations: $60–$120
• Compounded medication (sourced separately): $1,200–$2,400/year
• Total estimated annual cost: $1,440–$2,760

For the same patient at Trimi:

• Monthly subscription (semaglutide): $99 × 12 = $1,188/year
• All visits, adjustments, and oversight: included
• Total annual cost: $1,188

The Trimi savings range from $252 to $1,572 annually, depending on how frequently the Sesame patient needs visits and what their pharmacy charges.

What the Switch Looks Like in Practice

Step 1: Gather Your Information

Note your current medication, dose, injection schedule, and any recent labs or health changes. Your Trimi provider will use this to prescribe a continuation dose without requiring you to restart titration.

Step 2: Complete the Trimi Intake

Complete the Trimi online health assessment. Note that you are currently on GLP-1 therapy through another provider, and specify your current dose. The process takes under 15 minutes. No appointment is needed — a board-certified provider reviews asynchronously within 24 hours.

Step 3: Plan the Supply Bridge

Initiate the Trimi intake while you still have 2–3 weeks of supply from your current Sesame-prescribed pharmacy. Your Trimi shipment arrives within 5–8 business days in most cases, so a 2-week buffer is more than enough to avoid a gap. Learn more about preventing treatment gaps during provider transitions.

Step 4: Discontinue Sesame Services

Once your Trimi medication has arrived and your monthly schedule is established, you can stop booking Sesame appointments and cancel any recurring pharmacy order you had set up independently.

Busy Professionals: Why Asynchronous Telehealth Wins

Sesame Care's appointment model requires you to find a time in your schedule, book the visit, show up (even if virtually), and wait. For a busy professional managing a full calendar, this adds friction to what should be a background part of their health routine.

Trimi's asynchronous model means you complete your intake once, and your medication and oversight run automatically from that point. Questions or dose changes happen through messaging at whatever time is convenient — not during a 20-minute video slot you had to book two weeks in advance.

Frequently Asked Questions