Monitoring10 min readUpdated 2025-04-03

    GLP-1 Monthly Progress Report: What to Review and Share with Your Provider

    Create a comprehensive monthly GLP-1 progress report. Compile weight trends, side effects, measurements, and lab results to optimize your semaglutide or tirzepatide treatment.

    Monthly Report Template

    Compiling your weekly data into a monthly report gives you the big picture on your semaglutide or tirzepatide treatment. Here is what to include.

    Weight Summary

    Starting weight this month, ending weight, total change, and weekly trend line. Calculate your average weekly loss rate and compare to previous months.

    Measurement Changes

    Waist, hips, chest, arms, and thighs compared to last month. Total inches lost is often more motivating than pounds, especially during plateaus.

    Side Effect Trends

    Which side effects improved, worsened, or stayed the same. Average severity scores compared to previous months. Any new symptoms that appeared.

    Treatment Details

    Current dose, any dose changes, missed doses, and injection compliance. Note how dose changes correlated with side effects and weight loss rate.

    Quality of Life

    Energy levels, sleep quality, mood, exercise habits, and overall well-being. These non-scale victories are critical indicators of treatment success.

    Expected Monthly Progress by Phase

    Month 1 (Initiation)

    • 2-5 lbs lost on starting dose
    • Appetite reduction beginning
    • GI side effects most common

    Months 2-4 (Acceleration)

    • 4-8 lbs/month typical
    • Dose titrating upward
    • Side effects stabilizing

    Months 5-8 (Steady Loss)

    • 3-6 lbs/month at maintenance dose
    • Body composition improving
    • Health markers improving

    Months 9-12+ (Optimization)

    • 1-4 lbs/month as approaching goal
    • Maintenance planning begins
    • Focus shifts to sustainability

    Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Individual results vary. Consult your healthcare provider for personalized treatment guidance.

    Frequently Asked Questions

    What should be in my monthly GLP-1 report?

    Include total weight lost that month, total inches lost, average weekly weight loss rate, side effect trends, medication dose and any changes, notable improvements (energy, sleep, mood), and any concerns for your provider.

    How much weight should I lose per month on GLP-1?

    Most patients lose 4-8 pounds per month on semaglutide or tirzepatide. The first month may be slower during initial titration, while months 2-4 often show the fastest loss. Tirzepatide users may see slightly higher rates.

    When should I share my monthly report with my doctor?

    Share before scheduled appointments so your provider can review trends. If your report shows stalled progress, worsening side effects, or concerning patterns, schedule an earlier check-in to discuss adjustments.

    What if my monthly report shows a plateau?

    A single slow month is normal. If two consecutive monthly reports show minimal progress, review your nutrition, exercise, hydration, and sleep. Your provider may recommend a dose increase or other adjustments.

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    Sources & References

    1. Wilding JPH et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. NEJM 2021;384:989-1002.
    2. Jastreboff AM et al. Tirzepatide Once Weekly for the Treatment of Obesity. NEJM 2022;387:205-216.
    3. Lincoff AM et al. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. NEJM 2023;389:2221-2232.
    4. FDA Prescribing Information for Wegovy (semaglutide) and Zepbound (tirzepatide).

    What does the current clinical evidence support for GLP-1-based weight management?

    GLP-1 receptor agonists (semaglutide, tirzepatide) have Phase 3 RCT evidence for chronic weight management in adults with BMI ≥30 or BMI ≥27 with a weight-related comorbidity. Trimi offers compounded preparations of the same active ingredients at $99/month (semaglutide) and $125/month (tirzepatide) on the annual plan, prepared per individual prescription by 503A community sterile compounding pharmacies and reviewed by a US-licensed clinician through Beluga Health's 50-state physician network. Compounded preparations are not themselves FDA-approved as drugs; the active ingredients are FDA-approved in the corresponding brand finished products. Eligibility is determined by a licensed clinician.

    Phase 3 RCT evidence base: STEP 1 (NEJM 2021), SURMOUNT-1 (NEJM 2022), SELECT (NEJM 2023), FLOW (NEJM 2024)
    Trimi pricing: $99/month semaglutide / $125/month tirzepatide on annual plan
    Clinical review: Dr. Asad Niazi, MD MPH via Beluga Health 50-state network

    Key Takeaways

    • Compounded semaglutide and compounded tirzepatide are prepared per individual prescription by 503A community sterile compounding pharmacies (VialsRx — Texas State Board pharmacy license #35264 — and GreenwichRx). The active ingredients (semaglutide, tirzepatide) are FDA-approved in the corresponding brand finished products (Wegovy / Ozempic and Zepbound / Mounjaro respectively). Compounded preparations are not themselves FDA-approved as drugs.
    • Eligibility for GLP-1 treatment is determined by a licensed clinician: BMI ≥30, or BMI ≥27 with at least one weight-related comorbidity (type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, cardiovascular disease). Contraindications include personal/family history of medullary thyroid carcinoma, MEN 2 syndrome, pancreatitis, severe gastrointestinal disease, severe renal impairment, pregnancy, and breastfeeding.
    • Common GLP-1 receptor agonist adverse effects include nausea, vomiting, diarrhea, constipation, and gallbladder events. Most are mild-to-moderate and concentrated during dose escalation. Severe gastrointestinal symptoms causing dehydration can increase acute kidney injury risk and should be reported to the prescribing clinician.
    • Trimi's clinical review is coordinated by Dr. Asad Niazi, MD MPH through Beluga Health's 50-state physician network. Trimi pricing: $99/month for compounded semaglutide and $125/month for compounded tirzepatide on the annual plan; flat across all prescribed doses within whichever plan, with no enrollment / consultation / shipping fees.
    • This is general information based on the cited sources, not medical advice. Treatment decisions require evaluation by a licensed clinician familiar with your individual medical history.

    Medically Reviewed

    TMRT

    Trimi Medical Review Team

    Clinical review workflow for GLP-1 safety, dosing, and access content

    Team-based medical review process documented in Trimi's Medical Review Policy

    Last reviewed: October 14, 2025

    TCCT

    Written by Trimi Clinical Content Team

    Medical Writers & Healthcare Professionals

    Our clinical content team includes registered nurses, pharmacists, and medical writers who specialize in translating complex medical information into clear, actionable guidance for patients.

    Medically reviewed by Trimi Medical Review Team, Clinical review workflow for GLP-1 safety, dosing, and access content

    What real Trimi patients say

    Verbatim quotes from Trimi's Facebook and Reddit community reviews. First name and last initial preserved per editorial policy.

    21 lbs down in 6 weeks! So happy I started with you guys!

    Outcome: 21 lbs lost in 6 weeks

    Robyn Lynn CurtisFacebook
    Amazing company and care team support! Fast response time, no hidden fees and they actually care enough to work with you and your needs on your weight loss journey. Down 12.5 pounds in 2 months!

    Outcome: Down 12.5 lbs in 2 months

    Sarah MillerFacebook

    Editorial Standards

    Trimi publishes patient education using a medical-review workflow, source-based claim checks, and dated updates for fast-changing pricing, access, and safety topics.

    Review our Editorial Policy and Medical Review Policy for more details about sourcing, updates, and reviewer attribution.

    Scientific References

    1. Garvey WT, Mechanick JI, Brett EM, et al. (2024). American Association of Clinical Endocrinology / American College of Endocrinology Comprehensive Clinical Practice Guidelines for Medical Care of Patients with Obesity. Endocrine Practice.Read StudyDOI: 10.4158/EP161365.GL
    2. American Heart Association (2021). Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association. Circulation.Read StudyDOI: 10.1161/CIR.0000000000000973
    3. Apovian CM, Aronne LJ, Bessesen DH, et al. (2015). Pharmacological Management of Obesity: An Endocrine Society Clinical Practice Guideline. Journal of Clinical Endocrinology & Metabolism.Read StudyDOI: 10.1210/jc.2014-3415

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