How much muscle do you lose on semaglutide?

Studies show approximately 25-40% of weight lost on GLP-1 medications comes from lean mass (muscle) if no preventive measures are taken. However, with adequate protein intake and resistance training, muscle preservation improves dramatically—reducing lean mass loss to 10-20% of total weight lost.

How much protein should I eat on GLP-1 medication?

Aim for 1.2-1.6 grams of protein per kilogram of ideal body weight daily (roughly 25-40 grams per meal). Prioritize protein at every meal to preserve muscle mass during weight loss. Higher protein intake is especially important when appetite is suppressed.

What exercises prevent muscle loss on semaglutide?

Resistance training (weightlifting, bodyweight exercises, resistance bands) 2-3 times per week is most effective. Focus on compound movements like squats, deadlifts, push-ups, and rows. Progressive overload—gradually increasing weight or resistance—is key to maintaining and building muscle.

Can you build muscle while taking GLP-1 medication?

Yes, though it's challenging while in a caloric deficit. With adequate protein, consistent resistance training, and sufficient calorie intake, muscle maintenance and even modest gains are possible. Most people focus on muscle preservation during active weight loss, then shift to muscle building during maintenance.

Managing Muscle Loss on Semaglutide: Exercise and Nutrition Tips

The Muscle Loss Problem on GLP-1 Medications

GLP-1 medications like semaglutide and tirzepatide are incredibly effective for weight loss. But here's the challenge: not all weight loss is created equal. Losing fat is good. Losing muscle is problematic.

The Muscle Loss Problem on GLP-1 Medications

People Also Ask

How much muscle do you lose on semaglutide?

How much protein should I eat on GLP-1 medication?

What exercises prevent muscle loss on semaglutide?

Can you build muscle while taking GLP-1 medication?