TrimRx vs MEDVi (2026): Two GLP-1 Pricing Models Compared

What TrimRx and MEDVi each are

A quick disambiguation, because the names cause real confusion: TrimRx is not Trimi. They are separate, unaffiliated companies with different pricing, pharmacies, and provider networks , our TrimRx vs Trimi comparison covers that pairing in detail. This page compares TrimRx against MEDVi, the matchup people searching both brands actually want.

Both platforms are established players. MEDVi's own site claims more than 500,000 patients, and TrimRx was reviewed by U.S. News & World Report in June 2026, which credited it with fast onboarding, medication in about five to seven days for most patients, while noting slow customer service as its main weakness. Both companies describe legitimate clinical structures: an online intake, an asynchronous review by a licensed provider, and a prescription only when treatment is clinically appropriate. If you want the deeper single-provider write-ups, see is TrimRx legit and is MEDVi legit.

TrimRx vs MEDVi vs Trimi: side-by-side

TrimRx price observations were checked October 25, 2026 (UTC); its exact recurring period and all-in checkout total remain unverified. MEDVi figures remain dated August 2026 observations. The table does not establish matched-term savings.

Neither TrimRx nor MEDVi advertises a separate membership fee on compounded plans; MEDVi's brand-name routes use a separate membership-plus-medication structure. All three programs require a prescription from a licensed provider, and pricing at every provider only matters if a provider determines treatment is appropriate for you.

TrimRx's advertised starts and follow-up package quotes

Homepage starting offers, checked October 25, 2026 (UTC); Terms and conditions, checked October 25, 2026 (UTC); TrimRx review, October 1, 2026, secondary medicine mapping

TrimRx's homepage, checked October 25, 2026 (UTC), advertises GLP-1 from $179 and GLP-1+GIP from $279. Those starting offers are separate from its Terms prices. TrimRx's Terms, checked October 25, 2026 (UTC), list GLP-1 at $199 for the first month and $299 for a follow-up consultation package, and GLP-1+GIP at $349 for the first month and $399 for a follow-up consultation package. Mira's October 1, 2026 review identifies the GLP-1 program as semaglutide and GLP-1+GIP as tirzepatide. That medicine mapping is attributed secondary reporting; the primary GLP-1 price passage does not name semaglutide. The exact recurring billing period, calendar-month versus 4-week timing, required fees and all-in checkout charge were not verified. These public observations do not establish matched-term savings or a price at every dose. Confirm the medication, full charge, billing period and renewal terms in your own written quote.

Read the full covered term, amount due and refund conditions in the current written offer before prepaying. An introductory amount or a follow-up package quote alone does not establish your all-in ongoing cost.

Two more things worth knowing. First, TrimRx displays a LegitScript seal on its site, a meaningful verification signal in this category, and one you can confirm directly through LegitScript's checker. Second, TrimRx does not name its partner compounding pharmacy on its public pages, so ask which state-licensed pharmacy will prepare your prescription before you pay. Our TrimRx review and TrimRx cost guide cover the program in more depth.

MEDVi's model: a discounted first month, then the refill rate

MEDVi prices the opposite way. Instead of asking for months upfront, it discounts month one: compounded semaglutide injections start at $179 for the first month on MEDVi's own landing page in our August 2026 check, with $149 introductory offers reported by third-party reviews the same month, with no contract and free shipping. After the first month, 2026 pricing checks consistently list semaglutide refills at $299/month, a rate they describe as locked rather than rising with dose. The same checks put tirzepatide injections at $279 for the first month with ongoing rates reported at $399–$499/month depending on dose, and dissolvable GLP-1 tablets at $249. MEDVi's own pages carry the model's outline, a discounted start, no membership or hidden fees, and a money-back guarantee, but per-medication refill rates were not published on the public pages we checked, so confirm your exact rate before paying.

The refill rate, not the first-month rate, is the number to compare, because GLP-1 treatment is long-term: at listed rates, a first year of MEDVi semaglutide runs roughly $3,400–$3,470 ($149 or $179 plus eleven refills at $299), and third-party checks note MEDVi renews on 28-day cycles rather than calendar months, so a full year can include a thirteenth cycle. To MEDVi's credit, its structure is clean about what it excludes: compounded plans advertise no membership or hidden fees, the plan price covers the provider review, treatment plan, medication, and shipping, and HSA/FSA payment is accepted. Prescriptions are issued only after a consultation with an independent licensed provider, MEDVi works with provider networks including OpenLoop Health, and its pages state plainly that compounded medications are prepared by state-licensed pharmacies and are not FDA-approved.

MEDVi is month-to-month with no contract, which makes it the lower-risk way to start, and the more expensive way to continue. For the deeper breakdowns, see our MEDVi cost guide and MEDVi alternatives pages.

The third option: Trimi's flat annual pricing

Trimi's compounded semaglutide is $175 billed monthly and compounded tirzepatide is $235 billed monthly, with no multi-month commitment. Monthly plans renew automatically unless renewal is turned off; turning renewal off does not refund a term already paid for. Trimi's annual plans are $1,188 upfront for compounded semaglutide ($99/month equivalent) and $1,500 upfront for compounded tirzepatide ($125/month equivalent), with a 12-month commitment. The annual plans do not renew automatically. The price is the same at every prescribed dose. Plans include medication if prescribed, provider access and free next-day-air shipping, once prescribed, with medication typically arriving within 36 hours.

Trimi's annual plans are $1,188 upfront for compounded semaglutide ($99/month equivalent) and $1,500 upfront for compounded tirzepatide ($125/month equivalent), with a 12-month commitment. The annual plans do not renew automatically. Compare the full upfront charge, commitment and included services with your own current quote rather than inferring a price winner from introductory rates. Compounded preparations are prepared per individual prescription and are not FDA-approved as drugs; a licensed provider decides whether treatment is appropriate.

For wider context on what the whole market charges, our compounded semaglutide cost guide and compounded tirzepatide cost guide break down the four billing models used across US telehealth, and if you are already on treatment with TrimRx or MEDVi, switching GLP-1 providers requires provider review and does not promise a gap-free transition.

What the medication does, wherever you get it

The clinical evidence behind these programs comes from trials of the FDA-approved products. In the STEP 1 trial, semaglutide 2.4 mg weekly produced an average 14.9% body-weight reduction over 68 weeks alongside lifestyle changes (Wilding et al., New England Journal of Medicine, 2021). In SURMOUNT-1, tirzepatide produced an average 20.9% reduction at the highest dose over 72 weeks (Jastreboff et al., NEJM, 2022). Compounded preparations have not been studied in trials of their own, and individual results vary.

That is also why the FDA's guidance matters when comparing providers: per the FDA, compounded drugs are not reviewed for safety, effectiveness, or quality before marketing, and the agency's alert on unapproved GLP-1 drugs had logged 990 adverse event reports associated with compounded semaglutide as of May 31, 2026. The practical takeaway is not to avoid compounded treatment, it is to choose programs, like the three compared here, where a licensed provider prescribes and a verifiable state-licensed pharmacy prepares each prescription.

Five questions to ask TrimRx or MEDVi before you pay

Which should you choose?

Frequently asked questions