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    Am I a Candidate for GLP-1 Medication? A Self-Assessment Guide

    Wondering if semaglutide or tirzepatide could be right for you? This guide walks through the qualification criteria, contraindications, and questions to ask yourself before seeking treatment.

    Last updated: March 11, 202611 min read

    You have read about the results. You know people who have transformed their health with semaglutide or tirzepatide. Now you want to know: is this for me? While only a licensed healthcare provider can determine if GLP-1 medication is appropriate for your specific situation, this self-assessment guide helps you understand the general criteria.

    Medical Disclaimer

    This self-assessment is for informational purposes only and does not replace a medical evaluation. A licensed provider must evaluate your individual health profile before prescribing any medication.

    You May Be a Good Candidate If...

    Qualifying Factors

    • Your BMI is 30 or above (use an online BMI calculator)
    • Your BMI is 27-29.9 AND you have at least one of: type 2 diabetes, hypertension, high cholesterol, sleep apnea, heart disease, or PCOS
    • You are 18 years or older
    • You have tried lifestyle modifications (diet and exercise) with limited long-term success
    • You do not have any of the contraindications listed below
    • You are willing to make lifestyle changes alongside medication
    • You are not pregnant or planning to become pregnant in the near future

    You Should NOT Take GLP-1 If...

    Contraindications

    • Personal or family history of medullary thyroid carcinoma (MTC)
    • Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
    • Active pancreatitis or history of severe pancreatitis
    • Known allergy to semaglutide, tirzepatide, or any component
    • Currently pregnant or breastfeeding
    • Active eating disorder (anorexia nervosa or active bulimia)
    • Severe gastroparesis

    Conditions That Require Discussion

    Tell Your Provider About

    • History of pancreatitis
    • Gallbladder disease or gallstones
    • Kidney disease
    • Type 1 diabetes
    • Diabetic retinopathy
    • Current use of insulin or sulfonylureas
    • History of depression, anxiety, or suicidal thoughts
    • Planned surgery in the near future
    • History of eating disorders

    Having any of these conditions does not automatically disqualify you, but your provider needs to weigh the risks and benefits carefully and may require additional monitoring.

    Understanding Your BMI

    BMI (Body Mass Index) is calculated by dividing your weight in kilograms by your height in meters squared. While imperfect as a health metric, BMI is the standard clinical tool for determining GLP-1 eligibility. A BMI of 25 to 29.9 is classified as overweight. A BMI of 30 to 34.9 is Class I obesity. A BMI of 35 to 39.9 is Class II obesity. And a BMI of 40 or above is Class III (severe) obesity.

    For reference: a 5'6" person weighing 186 pounds has a BMI of 30. A 5'10" person weighing 209 pounds has a BMI of 30. Use any free online BMI calculator to check yours.

    Your Next Steps

    If you believe you may be a candidate based on this self-assessment, your next step is a medical evaluation with a licensed provider. Trimi's online health profile takes about 5 minutes to complete. A licensed provider reviews your information and determines if GLP-1 treatment is appropriate within 24 to 48 hours. If you are not a candidate, your provider will explain why and may suggest alternatives.

    There is no cost for completing the health profile, and no obligation to proceed if you are approved. Think of it as a free eligibility check from a real medical professional.

    The Bottom Line

    GLP-1 medications help millions of people achieve sustainable weight loss. If you meet the BMI criteria, do not have contraindications, and are ready to commit to treatment alongside healthy lifestyle changes, you are likely a good candidate. The only way to know for certain is to complete a medical evaluation.

    Find Out If You Qualify

    Complete a free health profile. Semaglutide from $99/mo, tirzepatide from $125/mo if approved.

    Check Eligibility

    Sources & References

    1. Wilding JPH et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. NEJM 2021;384:989-1002.
    2. Jastreboff AM et al. Tirzepatide Once Weekly for the Treatment of Obesity. NEJM 2022;387:205-216.
    3. Lincoff AM et al. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. NEJM 2023;389:2221-2232.
    4. FDA Prescribing Information for Wegovy (semaglutide) and Zepbound (tirzepatide).

    Am I a candidate for GLP-1 weight loss?

    GLP-1 weight-loss therapy eligibility per FDA prescribing information and Endocrine Society 2024 obesity guideline: adults aged 18 or older with BMI ≥30 (obesity) OR BMI ≥27 (overweight) with at least one obesity-related comorbidity (type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, non-alcoholic fatty liver disease, cardiovascular disease). To check your BMI: weight in kg / height in meters squared (or weight in lb / height in inches squared × 703). Absolute contraindications for ALL GLP-1 receptor agonists (semaglutide, tirzepatide, investigational retatrutide): personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Relative contraindications (require careful evaluation): pancreatitis history (rule out before starting; permanent contraindication after pancreatitis episode on therapy), gallbladder disease (rapid weight loss increases gallstone risk), severe gastrointestinal disease (gastroparesis, severe IBS, inflammatory bowel disease — flares possible), severe kidney disease (eGFR <15) requires nephrologist coordination, severe heart failure with reduced ejection fraction. Pregnancy contraindication: GLP-1 medications should be discontinued at least 2 months before attempting conception due to potential embryotoxicity (animal studies); discontinue immediately if pregnancy is detected. Breastfeeding: limited safety data; FDA generally recommends discontinuation. Pediatric eligibility: Wegovy is FDA-approved for adolescent obesity ages 12+ with BMI in age/sex 95th percentile; tirzepatide pediatric trials ongoing; compounded GLP-1 via telehealth typically restricted to adults 18+. Trimi Health adult eligibility (18+): conducts comprehensive medical history review at consultation including BMI verification, comorbidity assessment, contraindication screening — Trimi via Beluga Health 50-state US-licensed clinician network provides this evaluation as part of $99/month annual compounded semaglutide or $125/month annual compounded tirzepatide subscription (no upfront consultation fee). If you don't qualify for GLP-1 therapy based on contraindications, alternative weight-loss approaches include lifestyle counseling, behavioral therapy, alternative medications (phentermine short-term, naltrexone-bupropion), or bariatric surgery for severe cases.

    BMI ≥30 OR BMI ≥27 + comorbidity (T2D, HTN, dyslipidemia, OSA, NAFLD).
    Contraindicated: MTC/MEN 2 history, pancreatitis history, pregnancy.
    Trimi Beluga Health conducts eligibility review at consultation.

    Key Takeaways

    • Eligibility for GLP-1 weight-loss therapy per FDA and Endocrine Society 2024 guidelines: BMI ≥30 (obesity) OR BMI ≥27 with at least one obesity-related comorbidity (T2D, hypertension, dyslipidemia, sleep apnea, fatty liver).
    • Absolute contraindications: personal/family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), pancreatitis history (relative).
    • Pregnancy contraindication: discontinue ≥2 months before attempting conception.
    • Adults 18+; pediatric use limited to FDA-approved indications (Wegovy approved age 12+ for adolescent obesity).
    • Discuss medical history with prescribing clinician — Trimi via Beluga Health 50-state network conducts comprehensive eligibility review at no upfront cost.

    Medically Reviewed

    DMR

    Dr. Michael Rodriguez

    MD, FACP, Board Certified in Internal Medicine

    Internal Medicine & Weight Management

    Last reviewed: March 21, 2026

    TCCT

    Written by Trimi Clinical Content Team

    Medical Writers & Healthcare Professionals

    Our clinical content team includes registered nurses, pharmacists, and medical writers who specialize in translating complex medical information into clear, actionable guidance for patients.

    Medically reviewed by Dr. Michael Rodriguez, MD, FACP, Board Certified in Internal Medicine

    What real Trimi patients say

    Verbatim quotes from Trimi's Facebook and Reddit community reviews. First name and last initial preserved per editorial policy.

    It's only been 2 weeks since I've been taking the VialsRx meds from Trimi. The medication showed up pretty quickly (about 4 days after getting approval from Trimi prescriber) and I received 3 vials for my first 3 months on the subscription. For the price and convenience my take is that Trimi and VialsRx is good.

    Outcome: 4-day delivery; 3 vials for first 3 months; price + convenience verdict positive

    Really great customer service! Fast shipment.

    Outcome: Fast shipment

    Amy KeithFacebook

    Editorial Standards

    Trimi publishes patient education using a medical-review workflow, source-based claim checks, and dated updates for fast-changing pricing, access, and safety topics.

    Review our Editorial Policy and Medical Review Policy for more details about sourcing, updates, and reviewer attribution.

    Scientific References

    1. Eli Lilly and Company (2025). Zepbound (tirzepatide) prescribing information. U.S. Food and Drug Administration.Read Study
    2. Novo Nordisk (2025). Wegovy (semaglutide) prescribing information. U.S. Food and Drug Administration.Read Study
    3. The Endocrine Society (2024). Pharmacological Management of Obesity: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism.Read Study
    4. American Association of Clinical Endocrinology (2024). AACE Comprehensive Type 2 Diabetes Management Algorithm — Obesity. Endocrine Practice.Read Study

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